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Psychnptraining

Moclobemide (Manerix) Medication

The Reversible MAOI

Flexible and reversible mood support

Created By: Dr Padder

1,158,467 students

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ABOUT COURSE

This course offers comprehensive insight into Moclobemide, effective in major depressive disorder (MDD) with atypical features, with a favorable side effect profile compared to traditional MAOIs.

The curriculum covers essential topics for prescribers including:

  • Indications
  • Dosage and Administration
  • Mechanism of Action
  • Pharmacokinetics
  • Warnings
  • Drug Interactions
  • Contraindications
  • Augmentation Strategies
  • Recommended Lab Tests
  • Therapeutic Levels
  • Overdose Management
  • Tapering/Withdrawal
  • Use in Special Populations-
    • Pregnancy, 
    • Lactation, 
    • Renal Impairment, 
    • Hepatic Impairment, 
    • Cardiac Impairment, 
    • Elderly, 
    • Children and Adolescents
  • Important pearls based on years of practice.
  • This course aims to optimise the clinical proficiency of psychiatric nurse practitioners and other prescribers by providing the knowledge to prescribe and manage Moclobemide therapy effectively and safely.

LEARNING OBJECTIVES

Brand Names & Generic:
  • Learn about brand names under which Moclobemide is marketed.
  • Learn about different generic names under which Moclobemide is available in the market.
Indications:
  • Learn the FDA-approved uses and potential off-label applications of Moclobemide.
  • Know the dosages of all potential off-label uses.
Dosage and Administration:
  • Understand different medication forms and their administration.
  • Implement appropriate dosage and administration guidelines for Moclobemide in various clinical scenarios.
  • Learn how to dose Moclobemide correctly and identify usual dosage ranges.
Pharmacological Effects:
  • Explore the mechanisms of Moclobemide.
  • Understand how Moclobemide works in the brain to treat depression and other conditions.
  • Discuss the impact of Moclobemide on neurotransmitter levels and brain chemistry.
Pharmacokinetics:
  • Absorption: Understand how Moclobemide is absorbed in the body.
  • Distribution: Learn about the distribution of Moclobemide in the body.
  • Metabolism: Discuss the metabolism of Moclobemide.
  • Elimination: Understand how Moclobemide is eliminated from the body.
  • Half-life: Know the half-life of Moclobemide and its clinical significance.
Drug Interactions:
  • Identify common drug interactions with Moclobemide and strategies for managing them.
  • Understand the mechanisms through which these interactions occur.
  • Know which medications should be avoided with Moclobemide due to drug interactions.
Common Side Effects:
  • Learn about the most common side effects of Moclobemide.
  • Understand potential life-threatening side effects and how to manage them.
  • Educate patients on what to expect and how to manage side effects.
Contraindications:
  • Learn the conditions under which Moclobemide should not be used.
  • Understand the reasons why these conditions are contraindicated.
Best Augmenting Combos for Partial Response:
  • Learn about the best augmenting combinations for patients with partial response to Moclobemide.
  • Discover effective strategies for augmenting Moclobemide therapy.
  • Evaluate the efficacy and safety of common augmentation strategies.
  • Learn about recommended lab tests for safe and effective monitoring.
  • Identify necessary lab tests to monitor patients on Moclobemide.
  • Interpret lab results to guide treatment adjustments.
Therapeutic Monitoring:
  • Apply strategies for therapeutic monitoring to optimize treatment outcomes.
  • Know about the therapeutic blood levels for Moclobemide.
Overdose:
  • Understand the signs and symptoms of Moclobemide overdose.
  • Recognize early warning signs of overdose and effective management strategies.
Tapering/Withdrawal:
  • Apply best practices for tapering and withdrawal of Moclobemide to minimize withdrawal symptoms.
  • Follow the best protocols based on decades of clinical practice to safely taper Moclobemide.
  • Educate patients on the process and expected symptoms of tapering.
Usage with Special Populations:
  • Gain insights into the unique considerations for prescribing Moclobemide to special populations such as pregnancy, lactation, hepatic impairment, renal impairment, cardiac impairment, elderly, and children.
  • Tailor Moclobemide dosage for special populations considering their unique needs.
  • Understand the risks and benefits of Moclobemide use in these populations.
Important Pearls:
  • Learn about essential clinical pearls to enhance practice and ensure patient safety.
  • Understand the most important facts about Moclobemide based on decades of clinical practice.
  • Apply practical tips and experiences from clinical practice to improve patient outcomes.
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Flexible and reversible mood support

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