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Psychnptraining

Prochlorperazine (Compazine)Medication

The Multifunctional Antianxiety

Comprehensive care for anxiety and nausea

Created By: Dr Padder

1,158,467 students

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ABOUT COURSE

This course provides a unique perspective of Prochlorperazine, an antipsychotic medication also used to treat severe nausea and vomiting and an older anxiolytic.

The curriculum covers essential topics for prescribers including:

  • Indications
  • Dosage and Administration
  • Mechanism of Action
  • Pharmacokinetics
  • Warnings
  • Drug Interactions
  • Contraindications
  • Augmentation Strategies
  • Recommended Lab Tests
  • Therapeutic Levels
  • Overdose Management
  • Tapering/Withdrawal
  • Use in Special Populations-
    • Pregnancy, 
    • Lactation, 
    • Renal Impairment, 
    • Hepatic Impairment, 
    • Cardiac Impairment, 
    • Elderly, 
    • Children and Adolescents.
  • Important pearls based on years of practice.

This course aims to elevate the clinical expertise of psychiatric nurse practitioners and other prescribers by providing the knowledge to prescribe and manage Prochlorperazine therapy effectively and safely.

LEARNING OBJECTIVES

Brand Names & Generic:
  • Learn about brand names under which Prochlorperazine is marketed.
  • Learn about different generic names under which Prochlorperazine is available in the market.
Indications:
  • Learn the FDA-approved uses and potential off-label applications of Prochlorperazine.
  • Know the dosages of all potential off-label uses.
Dosage and Administration:
  • Understand different medication forms and their administration.
  • Implement appropriate dosage and administration guidelines for Prochlorperazine in various clinical scenarios.
  • Learn how to dose Prochlorperazine correctly and identify usual dosage ranges.
Pharmacological Effects:
  • Explore the mechanisms of Prochlorperazine.
  • Understand how Prochlorperazine works in the brain to treat anxiety and other conditions.
  • Discuss the impact of Prochlorperazine on neurotransmitter levels and brain chemistry.
Pharmacokinetics:
  • Absorption: Understand how Prochlorperazine is absorbed in the body.
  • Distribution: Learn about the distribution of Prochlorperazine in the body.
  • Metabolism: Discuss the metabolism of Prochlorperazine.
  • Elimination: Understand how Prochlorperazine is eliminated from the body.
  • Halflife: Know the half-life of Prochlorperazine and its clinical significance.
Drug Interactions:
  • Identify common drug interactions with Prochlorperazine and strategies for managing them.
  • Understand the mechanisms through which these interactions occur.
  • Know which medications should be avoided with Prochlorperazine due to drug interactions.
Common Side Effects:
  • Learn about the most common side effects of Prochlorperazine.
  • Understand potential life-threatening side effects and how to manage them.
  • Educate patients on what to expect and how to manage side effects.
Contraindications:
  • Learn the conditions under which Prochlorperazine should not be used.
  • Understand the reasons why these conditions are contraindicated.
Best Augmenting Combos for Partial Response:
  • Learn about the best augmenting combinations for patients with partial response to Prochlorperazine.
  • Discover effective strategies for augmenting Prochlorperazine therapy.
  • Evaluate the efficacy and safety of common augmentation strategies.
  • Learn about recommended lab tests for safe and effective monitoring.
  • Identify necessary lab tests to monitor patients on Prochlorperazine.
  • Interpret lab results to guide treatment adjustments.
Therapeutic Monitoring:
  • Apply strategies for therapeutic monitoring to optimize treatment outcomes.
  • Know about the therapeutic blood levels for Prochlorperazine.
Overdose:
  • Understand the signs and symptoms of Prochlorperazine overdose.
  • Recognize early warning signs of overdose and effective management strategies.
Tapering/Withdrawal:
  • Apply best practices for tapering and withdrawal of Prochlorperazine to minimize withdrawal symptoms.
  • Follow the best protocols based on decades of clinical practice to safely taper Prochlorperazine.
  • Educate patients on the process and expected symptoms of tapering.
Usage with Special Populations:
  • Gain insights into the unique considerations for prescribing Prochlorperazine to special populations such as pregnancy, lactation, hepatic impairment, renal impairment, cardiac impairment, elderly, and children.
  • Tailor Prochlorperazine dosage for special populations considering their unique needs.
  • Understand the risks and benefits of Prochlorperazine use in these populations.
Important Pearls:
  • Learn about essential clinical pearls to enhance practice and ensure patient safety.
  • Understand the most important facts about Prochlorperazine based on decades of clinical practice.
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Comprehensive care for anxiety and nausea

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