Return to course: Agomelatine (Valdoxan) Medication
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Agomelatine (Valdoxan) Medication
Lessons
Agomelatine Brand Name & Introduction
Agomelatine Indications
Agomelatine Dosage & Adminstration
Agomelatine Pharmacological Effects
Agomelatine Pharmacokinetics & Warning
Agomelatine Drug Interactions
Agomelatine Common Side Effects
Agomelatine Contraindication
Agomelatine Augmentation For Partial Response
Agomelatine Tapering Withdrawal
Agomelatine Recommended Lab Test & Overdose
Agomelatine Special Populations
Agomelatine Important Pearls
Agomelatine Quiz
Agomelatine PDF
Agomelatine Quiz
“This quiz will evaluate your knowledge about Agomelatine medication.”
Q1: Agomelatine acts on which two primary receptor types?
A) Melatonergic and serotonergic receptors
B) Dopaminergic and adrenergic receptors
C) GABAergic and glutamatergic receptors
D) Cholinergic and histaminergic receptors
Q2: Which of the following is a unique characteristic of Agomelatine compared to other antidepressants?
A) No sexual side effects
B) Significant weight gain
C) High risk of QT prolongation
D) Strong sedative effects
Q3: What is the recommended starting dose of Agomelatine for the treatment of depression?
A) 10 mg once daily
B) 25 mg once daily at bedtime
C) 50 mg once daily
D) 100 mg twice daily
Q4: Which of the following is a common side effect of Agomelatine?
A) Headache
B) Weight gain
C) Sexual dysfunction
D) Insomnia
Q5: Agomelatine should be used with caution in patients with which of the following conditions?
A) Hepatic impairment
B) Renal impairment
C) Cardiac arrhythmias
D) Hypertension
Q6: Which enzyme primarily metabolizes Agomelatine?
A) CYP2D6
B) CYP1A2
C) CYP3A4
D) CYP2C19
Q7: What is the black box warning associated with Agomelatine?
A) Increased risk of suicidal ideation in children and adolescents
B) Hepatotoxicity
C) QT prolongation
D) Serotonin syndrome
Q8: Which off-label use is commonly associated with Agomelatine?
A) Shift work sleep disorder
B) Chronic pain
C) Anxiety disorder
D) Obsessive-compulsive disorder
Q9: What should be monitored regularly during Agomelatine therapy?
A) Liver function tests (LFTs)
B) Renal function
C) Blood pressure
D) Electrocardiogram (ECG)
Q10: Agomelatine is contraindicated in patients taking which of the following medications?
Potent CYP1A2 inhibitors and MAOIs
SNRIs
Benzodiazepines
SARIs
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