Return to course: Bupropion (Wellbutrin, Zyban) Medication

Bupropion (Wellbutrin, Zyban) Medication

Lessons

Bupropion Brand Name & Introduction

Bupropion Indications

Bupropion Dosage & Adminstration

Bupropion Pharmacological Effects

Bupropion Pharmacokinetics & Warning

Bupropion Drug Interactions

Bupropion Common Side Effects

Bupropion Contraindication & Augmentation For Partial Response

Bupropion Recommended Lab Test & Overdose

Bupropion Tapering/Withdrawal

Bupropion Special Populations

Bupropion Important Pearls

Bupropion Quiz

“This quiz will evaluate your knowledge about Bupropion medication.”

Q1. Bupropion is classified as which type of antidepressant?

A) Norepinephrine-dopamine reuptake inhibitor (NDRI)

B) Selective serotonin reuptake inhibitor (SSRI)

C) Tricyclic antidepressant (TCA)

D) Monoamine oxidase inhibitor (MAOI)

Q2. What is the primary indication for Bupropion?

A) Major depressive disorder (MDD)

B) Bipolar disorder

C) Schizophrenia

D) Anxiety disorders

Q3. Which of the following is a common side effect of Bupropion?

A) Insomnia

B) Sedation

C) Weight gain

D) Sexual dysfunction

Q4. Which serious adverse effect is associated with Bupropion, particularly at high doses?

A) Seizures

B) Hepatotoxicity

C) Nephrotoxicity

D) Hypertension

Q5. Which enzyme is primarily responsible for the metabolism of Bupropion?

A) CYP2B6

B) CYP3A4

C) CYP2D6

D) CYP1A2

Q6. Bupropion is contraindicated in patients with which of the following conditions?

A) Seizure disorder

B) Controlled hypertension

C) Mild hepatic impairment

D) Hyperlipidemia

Q7. Which off-label use is commonly associated with Bupropion?

A) Smoking cessation

B) ADHD

C) MDD

D) Seasonal Affective Disorder (SAD)

Q8.What is the black box warning associated with Bupropion?

A) Increased risk of suicidal thoughts and behaviors in pediatric and young adult patients

B) Hepatotoxicity

C) Risk of serotonin syndrome

D) Risk of hypertensive crisis

Q9. Which augmentation strategy may be used with Bupropion for partial response in depression?

A) SSRIs

B) Antipsychotics

C) Lithium

D) All of the above

10. Which of the following is a serious drug interaction with Bupropion?

A) MAO inhibitors

B) Benzodiazepines

C) Beta-blockers

D) Antihistamines

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