Return to course: Dosulepin (Prothiaden) Medication

Dosulepin (Prothiaden) Medication

Lessons

Dosulepin Brand Name & Introduction

Dosulepin Indications

Dosulepin Dosage & Adminstration

Dosulepin Pharmacological Effects

Dosulepin Pharmacokinetics & Warning

Dosulepin Drug Interactions

Dosulepin Common Side Effects

Dosulepin Contraindication & Augmentation For Partial Response

Dosulepin Recommended Lab Test & Overdose

Dosulepin Tapering/Withdrawal

Dosulepin Special Populations

Dosulepin Important Pearls

Dosulepin Quiz

“This quiz will evaluate your knowledge about Dosulepin medication.”

Q1. Dosulepin belongs to which class of antidepressants?

A) Tricyclic antidepressants (TCAs)

B) Selective serotonin reuptake inhibitors (SSRIs)

C) Monoamine oxidase inhibitors (MAOIs)

D) Serotonin-norepinephrine reuptake inhibitors (SNRIs)

Q2. Which neurotransmitter systems are primarily affected by Dosulepin?

A) Serotonin and norepinephrine

B) Dopamine and serotonin

C) GABA and glutamate

D) Acetylcholine and norepinephrine

Q3. What is the starting dose of Dosulepin for treating depression?

A) 25 mg once daily

B) 50 mg once daily

C) 75 mg once daily

D) 100 mg once daily

Q4. Which serious side effect is associated with Dosulepin, particularly at high doses?

A) QT prolongation

B) Seizures

C) Hepatotoxicity

D) Nephrotoxicity

Q5. Dosulepin is contraindicated in patients with which of the following conditions?

A) Recent myocardial infarction

B) Controlled hypertension

C) Mild renal impairment

D) Hyperlipidemia

Q6. Which enzyme is primarily responsible for the metabolism of Dosulepin?

A) CYP2D6

B) CYP3A4

C) CYP1A2

D) CYP2C19

Q7. Which off-label use is commonly associated with Dosulepin?

A) Neuropathic pain

B) Psychosis

C) Sleep disorders

D) Attention deficit hyperactivity disorder (ADHD)

Q8. What is the black box warning associated with Dosulepin?

A) Increased risk of suicidal thinking and behavior in children, adolescents, and young adults

B) Risk of serotonin syndrome

C) Hepatotoxicity

D) Risk of hypertensive crisis

Q9. Which augmentation strategy may be used with Dosulepin for partial response in depression?

A) Antipsychotics

B) Mood stabilizers

C) Psychostimulants

D) All of the above

Q10. Which serious drug interaction should be avoided with Dosulepin?

A) MAO inhibitors

B) Benzodiazepines

C) Beta-blockers

D) Antihistamines

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