Isocarboxazid Quiz

Q1. Isocarboxazid belongs to which class of antidepressants?

A) Monoamine oxidase inhibitors (MAOIs)

B) Selective serotonin reuptake inhibitors (SSRIs)

C) Tricyclic antidepressants (TCAs)

D) Serotonin-norepinephrine reuptake inhibitors (SNRIs)

Q2. Which of the following foods must be avoided by patients taking Isocarboxazid to prevent hypertensive crisis?

A) Aged cheese

B) Fresh fruits

C) White bread

D) Chicken

Q3. What is the recommended starting dose of Isocarboxazid for treating depression?

A) 5 mg twice daily

B) 10 mg twice daily

C) 20 mg twice daily

D) 25 mg twice daily

Q4. Which side effect is commonly reported with Isocarboxazid use?

A) Orthostatic hypotension

B) Weight gain

C) Insomnia

D) Sexual dysfunction

Q5. Isocarboxazid should be used with caution in patients with which of the following conditions?

A) Hyperthyroidism

B) Renal impairment

C) Cardiac arrhythmias

D) All of the above

Q6. Which enzyme is primarily involved in the metabolism of Isocarboxazid?

A) Non-CYP based pathways

B) CYP3A4

C) CYP2D6

D) CYP1A2

Q7. What is the black box warning associated with Isocarboxazid?

A) Increased risk of suicidal thoughts and behaviors in children, adolescents, and young adults

B) Hepatotoxicity

C) QT prolongation

D) Serotonin syndrome

Q8. Which drug interaction is particularly concerning with Isocarboxazid due to the risk of serotonin syndrome?

A) SSRIs

B) Beta-blockers

C) Antihistamines

D) Antipsychotics

Q9. Which of the following conditions is Isocarboxazid not FDA-approved to treat?

A) Depression

B) Treatment-resistant depression

C) Panic disorder

D) Generalized anxiety disorder

Q10. What should be monitored regularly during Isocarboxazid therapy?

A) Liver function tests (LFTs)

B) Renal function test (RFTs)

C) Blood pressure

D) Complete blood count (CBC)

Isocarboxazid (Marplan) Medication